Now What?

• House and Cuddy finally pursue a romantic relationship, navigating the challenges of balancing their personal feelings with their professional lives at Princeton Plainsboro. Despite genuine efforts, House's selfishness and inability to change strain the relationship throughout the season. • When Cuddy faces a serious health scare, House struggles to be emotionally present for her, leading Cuddy to reevaluate her priorities. She ultimately breaks up with House, a devastating turning point that sends him into a destructive spiral of reckless behavior and emotional volatility. • Thirteen disappears from the team early in the season, and it's eventually revealed she spent the year in prison. House tracks her down and uncovers the truth behind her incarceration, deepening their complicated bond. Meanwhile, brilliant but morally rigid medical student Martha Masters temporarily joins the team, facing a career-defining crossroads before ultimately departing. • Taub's personal life unravels as he deals with the fallout of his infidelity, questions his wife's own relationships, re-enters the dating scene after their separation, and receives unexpected news that could change his life forever. • House begins secretly experimenting with an untested drug to treat his chronic leg pain, but discovers it causes fatal tumors. In a desperate and harrowing scene, he attempts surgery on himself and is forced to call Cuddy for help, underscoring how their bond persists even after the breakup. • Unable to cope with losing Cuddy, House's season-long emotional deterioration culminates in a shocking act of violence: he drives his car through Cuddy's dining room while she and others are inside, then flees to a beach — leaving his freedom, career, and relationships in ruins heading into Season 8.